| English or local name | Scientific name | Range | Last seen |
|---|---|---|---|
| Dwarf hutia | Mesocapromys nanus | Cuba | 1937 |
| Zuniga’s dark rice rat | Melanomys zunigae | Peru | 1940s |
| Lake Mackay hare-wallaby | Lagorchestes asomatus | Australia | 1940 – 1960 |
| Yavapai Arizona cotton rat | Sigmodon arizonae jacksoni | Arizona | 1916 |
| Desert bettong | Bettongia anhydra | Australia | 1930s |
| Wondiwoi tree-kangaroo | Dendrolagus mayri | Wandammen Peninsula | Rediscovered in 2018 |
| Western black rhinoceros | Diceros bicornis longipes | Cameroon | 2006 |
| Burrowing bettong (graii) | Bettongia lesueur graii | Australia | ? |
| White-footed rabbit-rat | Conilurus albipes | Australia | 1845 |
| Christmas island shrew | Crocidura trichura | Christmas Island, Australia | 1990s ? |
| Large Palau flying fox | Pteropus pilosus | Palau Islands, Caroline Islands | 1874 |
| Visagie’s golden mole | Chrysochloris visagiei | South Africa | ? |
| Vietnam mouse-deer | Tragulus versicolor | Vietnam | Rediscovered in 2019 |
| Samana hutia | Plagiodontia ipnaeum | Dominican Republic, Haiti | ? |
| Gloomy tube-nosed bat | Murina tenebrosa | Tsushima Island, Japan | 1960s |
| Torre’s cave rat | Boromys torrei | Cuba | 1500 ? |
| Anthony’s woodrat | Neotoma anthonyi | Isla Todos Santos | 1926 |
| Tacoma pocket gopher | Thomomys mazama tacomensis | Washington | 1962 |
| South-western banded hare-wallaby | Lagostrophus fasciatus albipilis | Australia | 1906 |
| Southern black rhinoceros | Diceros bicornis bicornis | South Africa, Namibia | around 1850 |
| South China tiger | Panthera tigris amoyensis | South China | 1990s ? |
| St. Vincent pygmy rice rat | Oligoryzomys victus | Saint Vincent | 1870s |
| Singapore whiskered bat | Myotis oreias | Singapore | 1840 ? |
| Sherman’s pocket gopher | Geomys pinetis fontanelus | Georgia | 1950 |
| Sherman’s short-tailed shrew | Blarina shermani | Florida | 1955 |
| Little Swan Island hutia | Geocapromys thoracatus | Little Swan Island | 1955 |
| Saudi gazelle | Gazella saudiya | Arabian Peninsula | 1980s |
| Sardinian wild boar | Sus scrofa meridionalis | Sardinia, Corsica | ? |
| Indefatigable Galápagos mouse | Nesoryzomys indefessus | Santa Cruz Island | 1934 |
| Zanzibar leopard | Panthera pardus adersi | Sansibar | Rediscovered in 2018 |
| Island deer mouse | Peromyscus maniculatus streatori | San Miguel Island | 1860s ? |
| San Martín Island woodrat | Neotoma martinensis | San Martín Island | 1950s |
| San Felipe hutia | Mesocapromys sanfelipensis | Cuba | 1978 ? |
| San Bernardino white-eared pocket mouse | Perognathus alticolus alticolus | Califonia | 1934 |
| Insular myotis | Myotis insularum | Samoa | 1860s |
| Santa Lucia giant rice rat | Megalomys luciae | Saint Lucia | 1881 |
| Red-bellied gracile mouse opossum | Cryptonanus ignitus | Argentinia | 1962 ? |
| Reed wolf | Canis lupus minor | Balkan Peninsula | 1900 ? |
| Lesser yellow bat | Scotophilus borbonicus | Madagascar, Réunion | End of the 19th century ? |
| Queen Charlotte Islands caribou | Rangifer tarandus dawsoni | Graham Island | 1908 |
| Puerto Rican nesophontes | Nesophontes edithae | Puerto Rico | 1500 ? |
| Puerto Rican long-nosed bat | Monophyllus plethodon frater | Puerto Rico | 1850 ? |
| Puerto Rican hutia | Isolobodon portoricensis | Dominican Republic, Haiti, Puerto Rico | 1500 ? |
| Puerto Rican flower bat | Phyllonycteris major | Puerto Rico | 1850 ? |
| Puebla deer mouse | Peromyscus mekisturus | Puebla, Mexico | 1940s |
| Portuguese ibex | Capra pyrenaica lusitanica | Portugal | 1892 |
| Pallid beach mouse | Peromyscus polionotus decoloratus | Florida | 1959 |
| (Viscacha) | Lagostomus crassus | Peru | 1500 ? |
| Dusky flying fox | Pteropus brunneus | Australia | 1859 |
| Pemberton’s deer mouse | Peromyscus pembertoni | San Pedro Nelasco Island | 1930s |
| Panay giant fruit bat | Acerodon lucifer | Panay | 1996 |
| Toolache wallaby | Notamacropus greyi | Australia | 1937 |
| Woylie | Bettongia penicillata penicillata | Australia | 1920s |
| Eastern elk | Cervus elaphus canadensi | Canada | 1877 |
| North America puma | Puma concolor cougar | Maine | 1938 |
| Arctic reindeer | Rangifer tarandus eogroenlandicus | Greenland | 1900 |
| Okinawa flying fox | Pteropus loochoensis | Okinawa | 19th century |
| Nullarbor dwarf bettong | Bettongia pusilla | Australia | 19th century |
| North-eastern black rhinoceros | Diceros bicornis brucii | Somalia, Ethiopia to Sudan | Early 20th century |
| Mongolian Argali | Ovis jubata | China | 1970s |
| Heslop’s pygmy hippo | Choeropsis liberiensis heslopi | Nigeria | 1945 or earlier |
| Nevis rice rat | Pennatomys nivalis | St. Kitts, Nevis | 1930s |
| Izenhood kangaroo mouse | Microdipodops megacephalus nexus | Nevada | 1980s |
| Newfoundland wolf | Canis lupus beothucus | Newfoundland | 1911 |
| Nelson’s rice rat | Oryzomys nelsoni | María Madre Island, Nayarit, Mexico | 1897 |
| Southern bog lemming | Synaptomys cooperi relictus | Nebraska | 1968 |
| Musser’s coryphomys | Coryphomys musseri | Timor | 1500 ? |
| Crescent nail-tail wallaby | Onychogalea lunata | Australia | 1956 |
| Merriam’s elk | Cervus elaphus merriami | USA (North) | 1900 |
| Marl bandicoot | Perameles myosuros | Australia | 20th century |
| Martinique muskrat | Megalomys desmarestii | Martinique | 1902 |
| Malabar large-spotted civet | Viverra civettina | India | 1980s |
| Robert’s lechwe | Kobus leche robertsi | Sambia | 20th century |
| Lord Howe long-eared bat | Nyctophilus howensis | Lord Howe Island | 1889 |
| Long-tailed hopping mouse | Notomys longicaudatus | Australia | 1970s |
| Short-tailed hopping mouse | Notomys amplus | Australia | 1896 |
| Cuban coney | Geocapromys columbianus | Cuba | 1500 ? |
| Lesser stick-nest rat | Leporillus apicalis | Australia | 1933 or 1970s |
| Western Cuban nesophontes | Nesophontes micrus | Cuba | 1500 ? |
| Kenya oribi | Ourebia ourebi kenyae | Kenya | 1925 |
| Kenai Peninsula wolf | Canis lupus alces | Kenai Peninsula | 1925 |
| Caucasian moose | Alces alces caucasicus | Europe (East), Asia Minor | ? |
| Caspian tiger | Panthera tigris virgata | Iran | 1960s |
| Carpathian wisent | Bison bonasus hungarorum | Carpathians | 1790 |
| Cape lion | Panthera leo melanochaitus | Natal | 1865 |
| Kansas bog lemming | Synaptomys cooperi paludis | Kansas | 1646 |
| California grizzly bear | Ursus arctos californicus | California | 1922 |
| Queen of Sheba’s gazelle | Gazella bilkis | Yemen | 1951 |
| Javan tiger | Panthera tigris sondaica | Java | 1980s |
| Japanese river otter | Lutra nippon | Shikoku | 1979 ? |
| Jamaican rice rat | Oryzomys antillarum | Jamaica | 1870s |
| Angel de la Guarda woodrat | Neotoma insularis | Angel de la Guardia Island, Baja California, Mexico | 1990s |
| Mitred horseshoe bat | Rhinolophus mitratus | Bihar, India | 1844 |
| Hokkaido wolf | Canis lupus hattai | Hokkaidō, Sakhalin | 1889 |
| Marcano’s solenodon | Solenodon marcanoi | Hispaniola | 1500 or later |
| Haitian nesophontes | Nesophontes zamicrus | Hispaniola | 1500 ? |
| Imposter hutia | Hexolobodon phenax | Dominican Republic, Haiti | 1500 ? |
| Gull Island vole | Microtus pennsylvanicus nesophilus | Great Gull Island, Long Island Sund | 1898 |
| Guam flying fox | Pteropus tokudae | Guam | 1968 |
| Guadalcanal rat | Uromys porculus | Guadalcanal | 1888 |
| Big-eared hopping mouse | Notomys macrotis | Australia | 1840s |
| Large Samoan flying fox | Pteropus coxi | Samoa | 1840 |
| New Zealand greater short-tailed bat | Mystacina robusta | Stewart Island, New Zealand (South Island) | 1967 |
| Oriente cave rat | Boromys offella | Cuba | 1500 ? |
| Greater Cuban nesophontes | Nesophontes major | Cuba | 1500 ? |
| St. Michel nesophontes | Nesophontes paramicrus | Hispaniola | 1500 ? |
| Gould’s mouse | Pseudomys gouldii | Australia | Rediscovered in 2021 |
| Goff’s southeastern pocket gopher | Geomys pinetis goffi | Florida | 1955 |
| Furnace Canyon hog-nosed skunk | Conepatus leuconotus figginsi | Colorado | 1933 |
| Togo mouse | Leimacomys buettneri | Togo | 1890 |
| Florida giant rat | Solomys salamonis | Salomonen | 20th century |
| Vespucci’s rodent | Noronhomys vespuccii | Fernando de Noronha | ? |
| Emma’s giant rat | Uromys emmae | Owi Island, Indonesia | 1940s |
| De Winton’s golden mole | Cryptochloris wintoni | South Africa | Rediscovered in 2023 |
| Darling Daowns hopping mouse | Notomys mordax | Australia | 1840s |
| Indian giant squirrel | Ratufa indica dealbata | India | 1945 |
| Bunker’s woodrat | Neotoma bunkeri | Coronados Islands, Baja California, Mexico | 1932 |
| South-western black rhinoceros | Diceros bicornis chobiensis | Namibia | ? |
| Chihuahuan meadow vole | Microtus pennsylvanicus chihuahuensis | Mexico | 1998 |
| Chadwick beach cotton mouse | Peromyscus gossypinus restrictus | Florida | 1938 |
| Seram bandicoot | Rhynchomeles prattorum | Seram | 1920s |
| Cebu warty pig | Sus cebifrons cebifrons | Cebu | 2000 |
| Cascade mountain wolf | Canis lupus fuscus | USA | 1940 |
| Capricorn rabbit-rat | Conilurus capricornensis | Australia | 1788 |
| Candango mouse | Juscelinomys candango | Brazil | 1960s |
| Buhler’s coryphomys | Coryphomys buehleri | Timor | 1500 ? |
| Great hopping mouse | Notomys robustus | Australia | 19th century |
| Blue-gray mouse | Pseudomys glaucus | Australia | 1956 |
| Caucasian wisent | Bison bonasus caucasicus | Caucasus | 1927 |
| Montane hutia | Isolobodon montanus | Dominican Republic, Haiti | 1500 ? |
| Sundarbans rhinoceros | Rhinoceros sondaicus inermis | Bangladesh, Assam, Myanmar | 1910 |
| Barbuda giant rice rat | Megalomys audreyae | Barbuda | 1600 ? |
| Barbados raccoon | Procyon lotor gloveralleni | Barbados | 1964 |
| Barbados rice rat | Megalomys georginae | Barbados | 19th century |
| Bernard’s wolf | Canis lupus bernardi | Canada | 1918 |
| Liverpool Plains striped bandicoot | Perameles fasciata | Australia | 1922 |
| Ethiopian amphibious rat | Nilopegamys plumbeus | Ethiopia | 1927 |
| Atalaye nesophontes | Nesophontes hypomicrus | Hispaniola | 1500 ? |
| Ash Meadows montane vole | Microtus montanus nevadensis | Nevada | 1933 |
| Aru flying fox | Pteropus aruensis | Aru Islands, Indonesia | 1990s ? |
| Camp Verde cotton rat | Sigmodon arizonae arizonae | Arizona | 1932 |
| Anatolian boar | Sus scrofa libycus | Turkey, Anatolia | ? |
| Alcorn’s pocket gopher | Pappogeomys alcorni | Mexico | 1998 ? |
| Glacier Bay water shrew | Sorex alaskanus | Alaska | 1970s |
| Northern Sumatran rhinoceros | Dicerorhinus sumatrensis lasiotis | Bangladesh, India, Myanmar | 20th century |
| Sicilian wolf | Canis lupus cristaldii | Sicily | 1928 or later |
| Big Thicket hog-nosed skunk | Conepatus leuconotus telmalestes | Texas | 1905 |
| Sea mink | Neogale macrodon | USA (East Coast) | 1860 |
| Japanese sea lion | Zalophus japonicus | Sea of Japan (Japan, Korea, Russia) | 1951 ? |
| Bubal hartebeest | Alcelaphus buselaphus buselaphus | North Africa | 1923 |
| Formosan clouded leopard | Neofelis nebulosa | Taiwan | 1983 |
| Maclear’s rat | Rattus macleari | Christmas Island, Australia | 1904 |
| Mexican grizzly bear | Ursus arctos horribilis | Mexico | 1964 |
| Pyrenean ibex | Capra pyrenaica pyrenaica | Spain, France, Andorra | 2000 |
| King genet | Genetta poensis | Ivory Coast, Congo, Liberia, Ghana, Bioko | 1946 |
| Bory’s white bat | Boryptera alba | Réunion | 1801 |
| Bali tiger | Panthera tigris sondaica (balica) | Bali | 1940s |
| Bramble Cay melomys | Melomys rubicola | Bramble Cay | 2009 |
| Christmas Island pipistrelle | Pipistrellus murrayi | Christmas Island, Australia | 2009 |
| Argentinean warrah | Dusicyon avus | South America | 17th or 20th century |
| Falkland Islands wolf | Dusicyon australis | Falkland Islands | 1876 |
| Insular cave rat | Heteropsomys insulans | Puerto Rico, Vieques | 1500 ? |
| Aurochs | Bos primigenius | Europe, Asia, North Africa, India | 1627 |
| Bluebuck | Hippotragus leucophaeus | South Africa | 1799 or 1800 |
| Sardinian pika | Prolagus sardus | Corsica, Sardinia | 1774 ? |
| Desert bandicoot | Perameles eremiana | Australia | 1943 |
| Montane monkey-faced bat | Pteralopex pulchra | Guadalcanal | 1990s ? |
| Kouprey | Bos sauveli | Cambodia, Laos, Vietnam | 1982 |
| Broad-faced potoroo | Potorous platyops | Australia | 1875 |
| Badlands bishorn sheep | Ovis canadensis auduboni | North America | 1925 |
| Darwin’s Galápagos mouse | Nesoryzomys darwini | Santa Cruz | 1930 |
| Bola Batu babirusa | Babyrousa bolabatuensis | Sulawesi | ? |
| Desert rat-kangaroo | Caloprymnus campestris | Australia | 1935 |
| Galápagos giant rat | Megaoryzomys curioi | Santa Cruz, Isabela | 20th century |
| Vietnamese rhinoceros | Rhinoceros sondaicus annamiticus | Vietnam | 2009 |
| Atlas bear | Ursus arctos crowtheri | North Africa | 1869 |
| Small Samoan flying fox | Pteropus allenorum | Samoa | 1856 |
| Bulldog rat | Rattus nativitatis | Christmas Island, Australia | 1903 |
| Giant fossa | Cryptoprocta spelea | Madagascar | 1658 ? |
| Small Mauritian flying fox | Pteropus subniger | Réunion, Mauritius | 1864 |
| Honshu wolf | Canis lupus hodophilax | Honshū | 1905 |
| Lemerle’s hippopotamus | Hippopotamus lemerlei | Madagascar | 1500 ? |
| Shomburgk’s deer | Rucervus schomburgki | Thailand | 1938 |
| Jamaican monkey | Xenothrix mcgregori | Jamaica | 18th century |
| Cape warthog | Phacochoerus aethiopicus aethiopicus | South Africa | 1870s |
| Emperor rat | Uromys imperator | Guadalcanal | 1888 |
| Eastern hare-wallaby | Lagorchestes leporides | Australia | 1890 |
| Pig-footed bandicoot | Chaeropus ecaudatus | Australia | 1907 |
| Caribbean monk seal | Monachus tropicalis | Caribbean | 1952 |
| Barbary lion | Panthera leo leo | North Africa | 1942 |
| Telefomin cuscus | Phalanger matanim | Papua New Guinea | 1998 ? |
| Giant vampire bat | Desmodus draculae | Central and South America | 1820 ? |
| Yunnan lar gibbon | Hylobates lar yunnanensis | China | 2000 |
| Steller’s sea cow | Hydrodamalis gigas | Bering Sea | 1768 |
| Quagga | Equus quagga quagga | Africa (South) | 1883 |
| Lesser bilby | Macrotis leucura | Australia | 1960s |
| Syrian wild ass | Equus hemionus hemippus | North Africa | 1929 |
| Florida red wolf | Canis rufus floridianus | USA | 1910 |
| Hispaniolan edible rat | Brotomys voratus | Hispaniola | 1546 |
| Sturdee’s pipistrelle | Pipistrellus sturdeei | Haha-jima Island, Japan | End of the 19th century |
| Ilin Island cloudrunner | Crateromys paulus | Ilin Island | 1653 |
| Thylacine | Thylacinus cynocephalus | Tasmania | 1936 |
| Red gazelle | Eudorcas rufina | Algeria, Morocco | 1894 |
| Baiji | Lipotes vexillifer | China | 2002 |
| South-eastern Spanish wolf | Canis lupus deitanus | Spain | 1930s |
| California gray wolf | Canis lupus furlongi | California | ? |
| Mogollon mountain wolf | Canis lupus mogollonensis | Texas, Mexico | ? |
| Texas Ggrey wolf | Canis lupus monstrabilis | Texas, Mexico | ? |
| Southern Rocky Mountain wolf | Canis lupus youngi | USA | 1940 |
| Hidden Forest Uinta chipmunk | Tamias umbrinus nevadensis | Nevada | 1960 |
| Large sloth lemur | Palaeopropithecus ingens | Madagascar | 1620 ? |
| Twisted-toothed mouse | Quemisia gravis | Dominican Republic, Haiti | 1550 |
| (Rice rat) | Ekbletomys hypenemus | Antigua, Barbuda | 1500 or later |
| Butterfly bandicoot | Perameles papillon | Australia | 1920 to 1960 |
| South-eastern striped bandicoot | Perameles notina | Australia | ? |
| Marysville California kangaroo rat | Dipodomys californicus eximius | California | 1983 |
| Dolphin Island Chisel-toothed kangaroo rat | Dipodomys microps russeolus | Dolphin Island | 1940s |
| Fish spring pocket gopher | Thomomys bottae abstrusus | Nevada | 1933 |
| San Antonio pocket gopher | Thomomys bottae curtatus | Nevada | 1931 |
| Harquahala Southern pocket gopher | Thomomys bottae subsimilis | Arizona | 1917 |
| Louie’s Western pocket gopher | Thomomys mazama louiei | Washington | 1956 |
| San Cristóbal Island rice rat | Aegialomys galapagoensis galapagoensis | San Cristóbal | 1835 |
| Madargascan dwarf hippoptamus | Hippopotamus madagascariensis | Madagascar | ? |
| Cuban fig-eating bat | Phyllops vetus | Kuba, Île des Pins | 1750 ? |
| Lemke’s hutia | Rhizoplagiodontia lemkei | Haiti | ? |
| Long-eared mouse | Pseudomys auritus | Australia | 19th century |
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